Studies supporting benefits of the program when administered by teachers who have received a 2-3 day training workshop with the developers:
Mahu, I. T., Doucet, C., O'Leary-Barrett, M., & Conrod, P. J. (2015). Can cannabis use be prevented by targeting personality risk in schools? 24-month outcome of the adventure trial on cannabis use: a cluster randomized controlled trial. Addiction, 110, 1625-1633.
Conrod, P. J., O'Leary-Barrett, M., Newton, N., Topper, L., Castellanos-Ryan, N., Mackie, C., & Girard, A. (2013). Effectiveness of a Selective, Personality-Targeted Prevention Program for Adolescent Alcohol Use and Misuse A Cluster Randomized Controlled Trial. JAMA Psychiatry, 70, 334-342.
Studies supporting the benefits of the program delivered by a psychologist or experienced special needs teacher:
Lammers J, Goossens F, Conrod P, Engels R, Wiers RW, Kleinjan M. (2017). Effectiveness of a selective alcohol prevention program targeting personality risk factors: Results of interaction analyses. Addictive Behaviors. 71:82-8.
Conrod, P. J., Castellanos-Ryan, N., & Mackie, C. (2011). Long-Term Effects of a Personality-Targeted Intervention to Reduce Alcohol Use in Adolescents. Journal of Consulting and Clinical Psychology, 79, 296-306.
The program has been adapted for use in Australia, and the benefits have been demonstrated in two published studies:
Teesson M, Newton NC, Slade T, Carragher N, Barrett EL, Champion KE, et al. Combined universal and selective prevention for adolescent alcohol use: A cluster randomized controlled trial. Psychological Medicine. 2017;47(10):1761-70.
Newton, N., Conrod, P., Slade, T., Carragher, N., Champion, K., Barrett, E., Kelly, E., Nair, N., Stapinski, L. & Teesson, M. (2016). The long-term effectiveness of a selective, personality-targeted prevention program in reducing alcohol use and related harms: a cluster randomized controlled trial. Journal of Child Psychology and Psychiatry, 57, 1056-1065.
A randomised controlled trial examining the effects of the program on the binge drinking behaviour of teenagers in the Netherlands found the program had little or no effect on reducing the overall prevalence of this behaviour among this group. However, longer term beneficial effects are promising i.e. reductions in the development of binge drinking over time. See the paper below for full details:
Lammers, J., Goossens, F., Conrod, P., Engels, R., Wiers, R. W., & Kleinjan, M. (2015). Effectiveness of a selective intervention program targeting personality risk factors for alcohol misuse among young adolescents: results of a cluster randomized controlled trial. Addiction, 110, 1101-1109.
The Preventure program is included in SAMSHA's National Registry of Evidence-based Programs and Practices (USA).